Before joining the CHE, Dr Lange worked at the Centre for Science Development of the Human Sciences Research Council (HSRC) and at the National Research Foundation (NRF). Dr Lange has a BA Honours degree from the University of Buenos Aires, an MA in African Studies from El Colegio de Mexico and a PhD in History from the University of the Witwatersrand. She was a high school teacher in the mid-1980s, and a senior lecturer at the University of Buenos Aires. She taught African history at Khanya College in Johannesburg, and has been on the academic staff of a Masters of Higher Education offered by the universities of the Western Cape and Cape Town. Dr Lange has been part of a number of task teams and reference groups in relation to higher education and to science and technology policies. She is a member of the Board of the International Network of Quality Assurance Agencies.
Dr Lange has published in English and Spanish on history and on higher education issues. She has co-authored several policy reports on science and technology, and on higher education. She is the author of a book on South African history.